Animal Genetics

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September, 2014
New test available for dogs. Please see Collie Eye Anomaly (CEA)

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March, 2014
Animal Genetics purchases an additional genetic analyzer (ABI3130xl) to handle increased demand and improve service.

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February, 2013
In a blind study published in The Journal of Avian Medicine and Surgery conducted by Dr. Geoff Olsen and Dr. Brian Speer, Animal Genetics / Avian Biotech was the only laboratory to get a perfect score on all positive and negative test results. One lab reported 8 out of ten negative samples as positive.

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January, 2013
Animal Genetics publishes 3rd paper on Avian Borna Virus in Avian Diseases. Please contact us for a copy.

Pearl Dilution

Description:

Pearl is a coat dilution modifier. One of the most recent equine color genes to be mapped for commercial genetic testing, it has only been confirmed in a few breeds and is generally considered to be one of the rarer of all color traits. The presence of the pearl gene has been confirmed in breeds of Iberian origin, such as the Lusitano and Purebred Spanish horse, and it is theorised to be present in the Spanish Mustang. Where found to be present in the American Quarter horse, pearl dilution is regularly referred to as the 'Barlink Factor.'

Pearl dilution is a recessive gene, and therefore will only affect the coat of the carrying horse if:

1) Two inherited copies of the gene are present. Horses carrying two copies of pearl will have a lightened coat, mane and tail, in addition to bright eye colors due to pigment changes caused by the gene.

2) The cream dilution gene is also present in the pearl-carrying horse. It has been confirmed that the dominant cream gene will activate the pearl phenotype if the two genes are present. Horses positive for both cream and pearl will exhibit a double-dilute phenotype, again with a highly pale coat color similar to that of horses that are homozygous for the cream gene.


Pearl dilution will not act if a horse is heterozygous for the trait but negative for the cream dilution gene, meaning that a single inherited copy of the pearl gene alone will not affect the carrier's phenotype. Heterozygous pearl horses may breed diluted offspring if bred to another pearl carrier or a cream dilute horse. The visual coat color changes caused by pearl dilution are based upon the foundation color of the horse - for example, the phenotype of a double-pearl bay will vary from the phenotype of a double pearl chestnut.

Test Results:

Animal Genetics offers DNA testing for the pearl gene. The genetic test verifies the presence of the pearl mutation and presents results as one of the following:

Prl/Prl Homozygous Horse is positive for pearl, and carries two inherited copies of the gene. The phenotype of the homozygous pearl horse will be of dilute appearance, regardless of the presence of cream dilution. The homozygous pearl specimen will pass the pearl gene to 100% of foals, but may only produce diluted offspring if bred to another pearl or cream carrier.
n/Prl Heterozygous Horse is positive for pearl, having inherited the trait from one parent. No visual change to carrying horse, except for in the additional presence of the cream dilution gene. The horse will pass the pearl dilution gene to approximately half of foals when bred.
n/n Negative Horse can be considered a non-carrier of the pearl gene.

    Submit a Sample for Testing:

    To submit a sample for testing please click on ORDER and download a sample submission form. Then follow the sample collection and submission instructions.

     

    Cost per sample is $25.00. Please see our Equine Fee Schedule for all equine testing rates.